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Estradiol Production

 

Click on name of hormone or red arrow to go to hormone or enzyme page.

 

Cholesterol
ê

 

DHEA-S
éâ

 

 

Pregnenolone è
ê

17 a-Hydroxy
pregnenolone
è
ê

DHEA è
ê

ß Androstenediol
ê

 

Progesterone è
ê

17 hydroxy-
progesterone
è
ê

Androstenedione è
ê

ß Testosterone
ê

 

11-Deoxy
corticosterone

ê

11-deoxycortisol
ê

Estrone è

ß Estradiol

 

Corticosterone
ê

Cortisol

ø

÷

ø ÷

 

18-Hydroxy
corticosterone

ê
Aldosterone

 

 

Estriol

 

 

Estradiol Production:

Estradiol is the most potent of the estrogens that occur naturally in the human body.

Pregnenolone and progesterone (and the "17-hydroxy" intermediates) are precursors to estradiol.

The androgens DHEA, androstenediol, androstenedione and testosterone are all estradiol

precursors.

Estrone is a precursor to estradiol.

 

Estriol is a metabolite of estrogens and androgens, and is not an estradiol precursor.

 

 

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