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Enzymes in the steroidogenic pathway.

 

20 a -hydroxylase, 22 hydroxylase & 20,22 desmolase

Cholesterol side-chain cleavage reaction

 

 

Pathway:

Cholesterol à Pregnenolone

 

Reaction: cholesterol side-chain cleavage (hydroxylation at C22 and C20 and cleavage of

C20-C22 bond)

 

Cofactors:

 

Inhibitors:  

 

Enzyme Synonyms: P450scc (cholesterol side-chain cleavage), CYP11A1

 

 

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