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Management of Menopause Type® Seminar

Module C: Objective Data

 

DETERMINING MENOPAUSE TYPE® WITH LAB TESTS

The 12 Menopause Types®

Recall that in menopause there are a number of possibilities regarding estradiol & progesterone:

 

Estradiol & progesterone may both be adequate.

 

Estradiol may be deficient.

 

Progesterone may be deficient.

 

Estradiol & progesterone may both be deficient.

Add to those four possibilities the fact that Testosterone may be normal, low, or high.

(Please review "Menopause Redefined")

 

The Twelve Types of Menopause are as noted:

 

Normal Testosterone

Low Testosterone

High Testosterone

Adequate

Estradiol,

Adequate Progesterone

Type 1
Adequate Estradiol, Adequate Progesterone,
Normal Testosterone

Type 2
Adequate Estradiol, Adequate Progesterone, Low Testosterone

Type 3
Adequate Estradiol, Adequate Progesterone,
High Testosterone

Estradiol Deficiency

Type 4
Estradiol Deficiency, Normal Testosterone

Type 5
Estradiol Deficiency,
Low Testosterone

Type 6
Estradiol Deficiency,
High Testosterone

Progesterone Deficiency

Type 7
Progesterone Deficiency, Normal Testosterone

Type 8
Progesterone Deficiency, Low Testosterone

Type 9
Progesterone Deficiency,
High Testosterone

Estradiol Deficiency, Progesterone Deficiency

Type 10
Dual Deficiency,
Normal Testosterone

Type 11
Dual Deficiency,
Low Testosterone

Type 12
Dual Deficiency,
High Testosterone

 

The following table outlines each menopause type, the hormone portrait revealed by tests, the associated risks, and the pages which should be reviewed in "What's Your Menopause Type?"

 

Menopause Type

Hormone Portrait
Revealed by Tests

Associated Risks

Pages

Type 1

Adequate Estradiol
Adequate Progesterone
Adequate Testosterone

Menopause Type® One does not have many of the health risks associated with other Menopause Types®.

83-87

Type 2

Adequate Estradiol
Adequate Progesterone
Low Testosterone

Health risks may include vulvar disorders, decreased muscle mass, depression, osteoporosis and angina pectoralis (chest pain).

87-96

Type 3

Adequate Estradiol
Adequate Progesterone
High Testosterone

Health risks may include blood sugar and insulin problems (insulin resistance), increased risk of endometrial cancer and heart disease.

96-101

Type 4

Low Estradiol
Adequate Progesterone
Adequate Testosterone

Health risks may include osteoporosis and heart disease, as well as memory problems. Since estradiol plays an important role in blood glucose metabolism, there is also increased risk of insulin resistance and blood sugar disorders. Risks associated with insulin resistance include increased risk of heart disease, diabetes and endometrial cancer.

104-111

Type 5

Low Estradiol
Adequate Progesterone
Low Testosterone

Health risks may include vulvar disorders, decreased muscle mass, depression, decreased mental function, osteoporosis and heart disease including angina pectoralis (chest pain). Since estradiol plays an important role in blood glucose metabolism, there is also increased risk of insulin resistance and blood sugar disorders. Risks associated with insulin resistance include increased risk of heart disease, diabetes and endometrial cancer.

111-119

Type 6

Low Estradiol
Adequate Progesterone
High Testosterone

Health risks may include heart disease. Since estradiol deficiency and excessive testosterone both play important roles in blood glucose metabolism, there is also increased risk of insulin resistance and blood sugar disorders. Risks associated with insulin resistance include increased risk of heart disease, diabetes and endometrial cancer.

119-124

Type 7

Adequate Estradiol
Low Progesterone
Adequate Testosterone

Health risks may include osteoporosis, high blood pressure and anxiety disorders.

127-133

Type 8

Adequate Estradiol
Low Progesterone
Low Testosterone

Health risks may include decreased muscle mass, osteoporosis, some forms of cancer and heart disease.

133-139

Type 9

Adequate Estradiol
Low Progesterone
High Testosterone

Health risks may include anxiety disorders; sleep disorders, endometrial hyperplasia or endometrial cancer and heart disease. Since excessive testosterone affects blood glucose metabolism, there is also increased risk of insulin resistance and blood sugar disorders. Risks associated with insulin resistance include increased risk of heart disease, diabetes and endometrial cancer.

139-147

Type 10

Low Estradiol
Low Progesterone
Adequate Testosterone

Health risks associated with Menopause Type® Ten may include osteoporosis, depression, and heart disease.

149-155

Type 11

Low Estradiol
Low Progesterone
Low Testosterone

Health risks may include vulvar disorders, decreased muscle mass, depression, osteoporosis and heart disease, including angina pectoralis (chest pain). Since estradiol deficiency can affect blood glucose metabolism, there is also increased risk of insulin resistance and blood sugar disorders. Risks associated with insulin resistance include increased risk of heart disease, diabetes and endometrial cancer.

155-162

Type 12

Low Estradiol
Low Progesterone
High Testosterone

Health risks may include osteoporosis and heart disease. Since estradiol deficiency and excessive testosterone both affect blood glucose metabolism, there is also increased risk of insulin resistance and blood sugar disorders. Risks associated with insulin resistance include increased risk of heart disease, diabetes and endometrial cancer.

162-167

 

Review of Clinical Significance

Each of these Menopause Types® has it's own clinical presentation, and it's own risk factors, based on the deficiency of estradiol, progesterone or testosterone, or excess of testosterone. In physiological menopause, a deficiency of any of these hormones may be contributory to osteoporosis or heart disease. A physiological excess of testosterone may be contributory to heart disease, diabetes and some forms of cancer. Physiological imbalances may also be responsible for hot flashes (flushes), insomnia, fatigue or other symptoms.

 

What's Next?

Next we will discuss how therapeutic interventions for the management of Menopause Types® will be effected by objective data, such as hormone tests.

 

 

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