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Understanding Hormone Restoration
by Joseph Collins, RN, ND |
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Hormone Function |
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The human body depends on hormones even before birth.
While in its mother’s womb, a child’s adrenal glands produced great amounts
of DHEA, which benefited both the baby and the mother. The levels of DHEA
decreased shortly after birth, only to increase again in late childhood
during a hormonal change called adrenarche (“adrenal beginning”), which
occurred a few years before puberty. With puberty, the gonads (ovaries or
testes) matured to their adult form. As the years pass, women will cease
having the monthly cycles that began in puberty, and move out of reproductive
years, in a transition called menopause. Each of these changes is normal, and
the body should make the transitions with relative ease. |
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When hormones do not function as they should, these
transitions become difficult. Some women go through menopause with great
ease, while others experience significant disruption in their quality of
life. Some men experience decreased testosterone function as they age.
Decreased function of insulin, adrenal hormones and thyroid hormones may be
experienced by men and woman of any age. |
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When hormones function properly there
is improved quality of life and decreased risks for many diseases. When they
do not function properly many symptoms and diseases could result. It is
widely accepted that low hormone levels are associated with disease and poor
quality of living. Hormone replacement therapies that are often employed
include estrogens, progesterone, testosterone, thyroid hormones, and insulin.
It is important to recognize that these substances are given specifically to replace normal hormones, for the most
part; they do not restore hormone
production. |
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It’s Not Just the Levels, It’s the Listening |
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An important breakthrough in
hormone health is the recognition that hormone levels do not, in and of themselves,
tell us how well the hormone is functioning. It is not uncommon for patients
with “normal” or even “high” levels of a specific hormone to have almost
every sign and symptom of low hormone function. The key word here is function. Just because there are
hormones that can be measured in the blood, saliva or urine, it does not mean
the hormones are functioning properly. What appears to be an inconsistency
between hormone levels, and the symptoms that a patient experiences is
actually a sign that the cells of the body “do not listen” to the hormones as
well as they should. The most well-known example of this insulin resistance,
a widely recognized condition in which there is plenty of insulin in the
blood, but the cells throughout the body are resistance to the insulin. Hormone restoration requires both the
support of tissues that make hormones, and the support of the cell response in every tissue that is affected by
hormones. Functional endocrinology always requires a more detailed analysis
of the physiological response to hormones, or how well cells “listen”
to each hormone. Cellular response is as important as the function of hormone
production. |
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Hormone Restoration |
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Hormone restoration is
accomplished by first supporting the biochemical pathways that create the
hormones. These pathways require a wide range of vitamins and minerals as
cofactors. At the same time, increase the ability of cells to “listen” by
increasing the amount of fatty acids, which improve cell membrane health. A
vitamin/mineral formulation and essential fatty acids are the Foundation Interventions. |
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The next course of action is to
use phytotherapeutics (herbs with therapeutic value) targeted to the specific
hormone that needs to have its function restored. The Endocrine Restoration Formulations may be chosen based on the
specific needs to restore optimal function to estrogens, progesterone,
testosterone, insulin and/or thyroid. Each of these formulations must be
compatible with each of the other formulations so that they work together
synergistically to address all of the hormone needs of an individual. |
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Through customized dosing, the
Foundational Interventions and Endocrine Restoration Formulations can
effectively restore optimal hormone function by directly supporting the function
of hormone producing tissues, and the function of tissues throughout the body
that respond to hormones. In those situations when it is not possible to
achieve full restoration, the Foundational Interventions and Endocrine
Restoration Formulations are able to support at least partial function. If
the partial restoration required that some hormones be prescribed, the
partial restoration invariably is effective enough to allow much lower
dosages of hormones, and much better clinical outcome from the lower dosage.
Before hormone replacement therapy is chosen whether it is traditional (HRT)
or bioidentical (BHRT), Hormone
Precursors & Metabolites should always be considered, as they are
most often able to complete the hormone restoration, when used in conjunction
with Foundational Interventions and Endocrine Restoration Formulations. |
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Foundational
Interventions: |
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Lifestyle Management is Critical for Restoration of Optimal Hormone Function |
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Since lifestyle stress has a great
impact on the endocrine system, appropriate diet, exercise, rest, sleep,
recreation, social interactions, hydration, and detoxification are important
issues to address when first endeavoring to restore optimal hormone function. |
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Vitamins & Minerals are Foundation Cofactors for All Hormone
Production |
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Vitamins, minerals, trace minerals
and other trace nutrients are critical cofactors for the production and
metabolism of all hormones. An effective dosage of these hormone supporting
nutrients should be taken on a daily bases as foundation nutrients. Keeping
hormone supporting nutrients separate from the actual herbal formulation
allows clinicians to adjust the dosage of phytotherapeutic agents without the
risks of toxicity that would result if a specific mineral were placed within
a hormone specific formulation. By not adding zinc and copper to herbal
formulations, clinicians can adjust the dosage without concerns about zinc
becoming antagonists to steroidogenic pathway enzymes. Use a formulation that
has the right proportions of vitamins, minerals, trace elements, and other
nutrients to support optimal endocrine health, without danger of toxic
build-up or other side effects It also provides significant antioxidant
support, which is required by adrenal, gonadal and thyroid tissue. |
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Docosahexaenoic Acid (DHA) is the Fatty
Acid that Improves Hormone Signaling |
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DHA improves cell membrane health
by changing the lipid structure of the membrane in such a way as to actually
improve the ability of the cell to receive hormone signals. It also affects
the movement of molecules in the cell, affecting organelles within the cell
such as the mitochondria, the principal energy source of the cell. Increasing
DHA in the mitochondria through nutraceutical support improves the ability of
mitochondria to create cellular energy, and to carry out the message that it
received from the hormone. The high DHA:EPA ratio is critical for cell
membrane health |
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Endocrine
Restoration Formulations : |
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Based on the needs of each individual,
endocrine restoration formulations may be chosen to restore optimal function
of estrogens, progesterone, testosterone, insulin and/or thyroid. Since
excessive testosterone may have to be restored to safer levels, there may be
a need to use an endocrine restoration formulation that eases the signs and
symptoms of excessive testosterone. |
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The six endocrine restoration
formulations are designed to: |
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Support Estrogen Function by improving endogenous estrogen function |
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Support Progesterone Function by improving endogenous progesterone production and function |
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Support Testosterone Function by improving endogenous testosterone
production and function |
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Support Calmer Testosterone Function by easing signs and symptoms of
excessive testosterone |
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Support Thyroid Function by improving endogenous thyroid production and
function |
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Support Insulin Function by improving endogenous insulin production and
function |
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Hormone Precursors &
Metabolites before any HRT |
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Use “Precursors” & Metabolites Before any form of HRT – Which is
the Last Course of Action |
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Before hormone replacement therapy
is chosen whether it is traditional (HRT) or bioidentical (BHRT), weaker
hormones such as pregnenolone, DHEA, and/or the metabolite 7-keto-DHEA should
be considered. There will be situations where restoration of optimal hormone
function cannot be achieved with lifestyle, nutraceutical and phytoceutical
interventions alone. In those cases, the use of pregnenolone, DHEA, and/or
7-keto-DHEA can support the hormone producing pathways through
supplementation instead of replacement. Since DHEA, pregnenolone and
7-keto-DHEA have physiological actions of their own, and provide benefits
independent of BHRT, they increase the efficacy of BHRT if needed, and will
allow clinicians to prescribe much lower dosages with increased success. |
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♦These
statements have not been evaluated by the Food and Drug Administration. |
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YourMenopauseType.com, Inc. |
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